UBE2N Antibody
Code | Size | Price |
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PSI-27-794-100ul | 100ul | £609.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Canine (dog)
- Fish
- Fly
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store UBE2N antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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Further Information
Additional Names:
UBE2N, MGC131857, MGC8489, UBC13, UbcH-ben, UbcH13, HEL-S-71
Application Note:
UBE2N antibody can be used for detection of UBE2N by ELISA at 1:1562500. UBE2N antibody can be used for detection of UBE2N by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
UBE2N encodes a member of the E2 ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.
Background References:
- Zhang, M., (2005) Mol. Cell 20 (4), 525-538.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UBE2N.
NCBI Gene ID #:
7334
NCBI Official Name:
ubiquitin-conjugating enzyme E2N
NCBI Official Symbol:
UBE2N
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
17 kDa
Protein Accession #:
NP_003339
Protein GI Number:
4507793
Purification:
Antibody is purified by protein A chromatography method.
Swissprot #:
P61088
User NOte:
Optimal dilutions for each application to be determined by the researcher.