CCL3 Antibody
| Code | Size | Price |
|---|
| PSI-45-379-0.1mg | 0.1mg | £505.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.
Documents
Further Information
Additional Names:
CCL3, chemokine (C-C motif) ligand 3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3, LD78 alpha beta, Small inducible cytokine A3, small inducible cytokine A3 (homologous to mouse Mip-1a), CCL3L1, LD78, 464.2, SCYA3L, G0S19-2, SCYA3L1, D17S1718, LD78BETA, MGC12815, chemokine (C-C motif) ligand 3-like 1, small inducible cytokine A3-like 1, MIP-1aP, MGC104178, MGC182017, MIP1AP
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Preliminary experiments gave bands at approx 26+28kDa (doublet) and 40kDa in Human Bone Marrow and Spleen lysates after 0.1ug/ml antibody staining.The 26+28kDa doublet was also found in Human Lymph Node and in Tonsil lysates. Please note that currently we cannot find an explanation in the literature for the bands we observe given the calculated size of 10.2kDa according to NP_066286.1. The detected bands were successfully blocked by incubation with the immunizing peptide (and BLAST results with the immunizing peptide sequence did not identify any other proteins to explain these bands). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Background References:
- Gonzalez E, Kulkarni H, Bolivar H, Mangano A, Sanchez R, Catano G, Nibbs RJ, Freedman BI, Quinones MP, Bamshad MJ, Murthy KK, Rovin BH, Bradley W, Clark RA, Anderson SA, O'connell RJ, Agan BK, Ahuja SS, Bologna R, Sen L, Dolan MJ, Ahuja SK. The Influence of CCL3L1 Gene-Containing Segmental Duplications on HIV-1/AIDS Susceptibility. Science. 2005 Jan 6;
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human
Immunogen:
The immunogen for this antibody is: C-EWVQKYVSDLELSA
NCBI Gene ID #:
6348; 6349
NCBI Official Name:
chemokine (C-C motif) ligand 3
NCBI Official Symbol:
CCL3L1; CCL3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_002974.1, NP_066286.1
Protein GI Number:
4506843
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer ,Infectious Disease
SPECIFICITY:
Please note this product is expected to recognize the products of 2 different genes which are almost identical.
Swissprot #:
P10147