ProSci

DYX1C1 Antibody

Product Code:
 
PSI-45-511
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Caprine (Goat)
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Aliquot and store at -20˚C. Minimize freezing and thawing.
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45-511 staining (0.1ug/ml) of COS1 cell lysates: untransfected (left lane) and transfected with full length recombinant Human DYX1C1 (right lane). Data kindly provided by Wang and LoTurco, University of Connecticut, USA.
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45-511 staining (0.1ug/ml) of COS1 cell lysates: untransfected (left lane) and transfected with full length recombinant Human DYX1C1 (right lane). Data kindly provided by Wang and LoTurco, University of Connecticut, USA.

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PSI-45-511-0.1mg0.1mg£626.00
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This product comes from: United States.
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Further Information

Additional Names:
DYX1C1, DYX1, EKN1, DYXC1, FLJ37882, dyslexia susceptibility 1 candidate 1, MGC70618, RD
Application Note:
Peptide ELISA: antibody detection limit dilution 1:16000.Western Blot:Lysates of COS1 transfected with full length recombinant Human DYX1C1 gave bands at approx 48kDa after 0.1ug/ml antibody staining. In addition, a minor band of 24kDa is detected consistent with observations with N-terminal specific antibodies (unpublished data, LoTurco, Connecticut, USA). The 75kDa band is visible in the non-transfected COS1 also (first lane) and is therefore non-specific. We call for caution when this product is used in other assays than Western blot. Data kindly provided by Wang and LoTurco, University of Connecticut, USA.Immunohistochemistry:In paraffin embedded Human Cerebral Cortex shows cytoplasm staining in some of the neuronal cells. Recommended concentration, 5-10ug/ml.
Background References:
  • Taipale M, Kaminen N, Nopola-Hemmi J, Haltia T, Myllyluoma B, Lyytinen H, Muller K, Kaaranen M, Lindsberg PJ, Hannula-Jouppi K, Kere J. A candidate gene for developmental dyslexia encodes a nuclear tetratricopeptide repeat domain protein dynamically regulated in brain. Proc Natl Acad Sci USA. 2003 Sep 30;100(20):11553-8. Epub 2003 Sep 03.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat
Immunogen:
The immunogen for this antibody is: C-KIRNVIQGTELKS
NCBI Gene ID #:
161582
NCBI Official Name:
dyslexia susceptibility 1 candidate 1
NCBI Official Symbol:
DYX1C1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_570722.2
Protein GI Number:
75677570
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
This antibody is expected to recognise only one of the three reported isoforms (NP_570722.2, isoform a).
Swissprot #:
Q8WXU2