Fibrillin 2 Antibody

ProSci
Product Code: PSI-45-593
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-45-593-0.1mg0.1mg£505.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Further Information

Additional Names:
FBN2, fibrillin 2 (congenital contractural arachnodactyly), HGNC:3604, CCA , fibrillin 2, fibrillin 5
Application Note:
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Preliminary experiments gave an approx 30-35kDa band in human placenta lysates after 0.3 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 315kDa according to NP_001990.2. The 30-35kDa band was successfully blocked by incubation with the immunizing peptide.
Background References:
  • Quondamatteo F, Reinhardt DP, Charbonneau NL, Pophal G, Sakai LY, Herken R. Fibrillin-1 and fibrillin-2 in human embryonic and early fetal development. Matrix Biol. 2002 Dec;21(8):637-46.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human, Dog, Cow
Immunogen:
The immunogen for this antibody is: KELKKLEESNEDDC
NCBI Gene ID #:
2201
NCBI Official Name:
fibrillin 2
NCBI Official Symbol:
FBN2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001990.2
Protein GI Number:
66346695
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
Swissprot #:
P35556