GAB2 Antibody

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ProSci
Product Code: PSI-45-645
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-45-645-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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45-645 (0.5ug/ml) staining of K562 cell lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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45-645 (0.5ug/ml) staining of K562 cell lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Documents

Further Information

Additional Names:
GAB2, GRB2-associated binding protein 2, KIAA0571, Grb2-associated binder 2
Application Note:
Peptide ELISA: antibody detection limit dilution 1:64000.Western Blot:Approx 80kDa band observed in lysates of cell line K562 (calculated MW of 74.5kDa according to NP_536739.1). Recommended concentration: 0.5-1.5ug/ml.
Background References:
  • Bentires-Alj M, Gil SG, Chan R, Wang ZC, Wang Y, Imanaka N, Harris LN, Richardson A, Neel BG, Gu H. A role for the scaffolding adapter GAB2 in breast cance Nat Med. 2006 Jan;12(1):114-21. Epub 2005 Dec 20.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog
Immunogen:
The immunogen for this antibody is: C-QVDKEKTQALQN
NCBI Gene ID #:
9846
NCBI Official Name:
GRB2-associated binding protein 2
NCBI Official Symbol:
GAB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_536739.1, NP_036428.1
Protein GI Number:
18105042
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
This antibody is expected to recognize both reported isoforms (NP_536739.1; NP_036428.1).
Swissprot #:
Q9UQC2