GULP1 Antibody

ProSci
Product Code: PSI-45-716
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-45-716-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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45-716 staining (0.2ug/ml) of Human Placenta lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.
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45-716 staining (0.2ug/ml) of Human Placenta lysate (RIPA buffer, 30ug total protein per lane). Primary incubated for 1 hour. Detected by chemiluminescence.

Further Information

Additional Names:
CED-6, GULP1, CED-6 protein, GULP, engulfment adaptor PTB domain containing 1, CED6, FLJ31156, OTTHUMP00000205908, OTTHUMP00000205909, OTTHUMP00000205911, PTB domain adaptor protein CED-6, engulfment adapter protein
Application Note:
Peptide ELISA: antibody detection limit dilution 1:64000.Western Blot:Approx 35kDa band observed in Human Placenta lysates (calculated MW of 34.5kDa according to NP_057399.1). Recommended concentration: 0.2-0.6ug/ml. An additional band of unknown identity was also consistently observed at approx.46kDa. This band was successfully blocked by incubation with the immunising peptide.Immunohistochemistry:In paraffin embedded Human Kidney shows staining of cytoplasm, stronger in a selection of epithelial cells of distal convoluted tubules. Recommended concentration: 5-10 ug/ml.
Background References:
  • Su HP, Nakada-Tsukui K, Tosello-Trampont AC, Li Y, Bu G, Henson PM, Ravichandran KS. Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP). J Biol Chem. 2002 Apr 5;277(14):11772-9. Epub 2001 Nov 29.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog
Immunogen:
The immunogen for this antibody is: EGTVFCLDPLDSRC
NCBI Gene ID #:
51454
NCBI Official Name:
GULP, engulfment adaptor PTB domain containing 1
NCBI Official Symbol:
GULP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_057399.1
Protein GI Number:
7705318
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
.
Swissprot #:
Q9UBP9