INCA Antibody

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ProSci
Product Code: PSI-42-270
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-42-270-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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42-270 (0.5ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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42-270 (0.5ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Documents

Further Information

Additional Names:
INCA, CARD17, caspase recruitment domain family, member 17, Inhibitory CARD, caspase recruitment domain-containing protein 17, caspase-1 inhibitor INCA, inhibitory caspase recruitment domain (CARD) protein, inhibitory caspase recruitment domain protein
Application Note:
Peptide ELISA: antibody detection limit dilution 1:8000.Western Blot:Approx 15kDa double band observed in Human Kidney and Lung lysates (calculated MW of 11.9kDa according to NP_001007233.1). Recommended concentration: 0.5-1.5ug/ml.
Background References:
  • Lamkanfi M, Denecker G, Kalai M, D'hondt K, Meeus A, Declercq W, Saelens X, Vandenabeele P INCA, a novel human caspase recruitment domain protein that inhibits interleukin-1beta generation J Biol Chem. 2004 Dec 10;279(50):51729-38
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: C-NHLTTQDSQIVLPS
NCBI Gene ID #:
440068
NCBI Official Name:
caspase recruitment domain family, member 17
NCBI Official Symbol:
INCA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001007233.1
Protein GI Number:
55925612
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Apoptosis
SPECIFICITY:
.
Swissprot #:
Q5XLA6