KU70 Antibody
| Code | Size | Price |
|---|
| PSI-45-817-0.1mg | 0.1mg | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.
Documents
Further Information
Additional Names:
XRCC6, KU70, X-ray repair complementing defective repair in Chinese hamster cells 6 (Ku autoantigen, 70kDa) , CTC75, CTCBF, G22P1, ML8, TLAA , ATP-dependent DNA helicase II, 70 kDa subunit, CTC box binding factor 75 kDa subunit, Ku autoantigen p70 subunit, OTTHUMP00000028581, thyroid autoantigen 70kD (Ku antigen), thyroid autoantigen 70kDa (Ku antigen), thyroid-lupus autoantigen p70
Application Note:
Peptide ELISA: antibody detection limit dilution 1:2000.Western Blot:Approx 70kDa band observed in lysates of cell lines A431, HeLa and HepG2 (calculated MW of 69.8kDa according to NP_001460.1). In transfected HEK293 transiently expressing KU70 a band of approx. 70kDa is observed. This band is not observed in the non-transfected HEK293.Recommended concentration: 0.1-0.3ug/ml.
Background References:
- Ribes-Zamora A, Mihalek I, Lichtarge O, Bertuch AA. Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions. Nat Struct Mol Biol. 2007 Apr;14(4):301-307. Epub 2007 Mar 11.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
The immunogen for this antibody is: YKTEGDEEAEEEQ-C
NCBI Gene ID #:
2547
NCBI Official Name:
X-ray repair complementing defective repair in Chinese hamster cells 6
NCBI Official Symbol:
XRCC6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001460.1
Protein GI Number:
4503841
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
SPECIFICITY:
.
Swissprot #:
P12956