MLX Antibody

ProSci
Product Code: PSI-42-272
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-42-272-0.1mg0.1mg£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Caprine (Goat)
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
Aliquot and store at -20˚C. Minimize freezing and thawing.

Images

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42-272 (3.8ug/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

42-272 (3.8ug/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Further Information

Additional Names:
MLX, MAX-like protein X, MAD7, MXD7, TCFL4, bHLHd13, BigMax protein, MAX-like bHLHZIP protein, transcription factor-like 4, transcription factor-like protein 4
Application Note:
Peptide ELISA: antibody detection limit dilution 1:128000.Western Blot:Preliminary experiments in Human, Mouse and Rat Liver lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml). We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?Immunohistochemistry:In paraffin embedded Human Placenta shows nuclear stsaining of trophoblasts. Recommended concentration, 2.5-3.8ug/ml.
Background References:
  • Stoltzman CA, Peterson CW, Breen KT, Muoio DM, Billin AN, Ayer DE, Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression. Proceedings of the National Academy of Sciences of the United States of America 2008 May 105 (19): 6912-7.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Cow
Immunogen:
The immunogen for this antibody is: C-QIVKAHQDNPHEGED
NCBI Gene ID #:
6945
NCBI Official Name:
MLX, MAX dimerization protein
NCBI Official Symbol:
MLX
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_937848.1, NP_937847.1, NP_733752.1
Protein GI Number:
38201614
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Transcription ,Cancer
SPECIFICITY:
This antibody is expected to recognize all three reported isoforms (NP_937848.1; NP_937847.1; NP_733752.1).
Swissprot #:
Q9UH92