STAT3 Antibody

Contact us
ProSci
Product Code: PSI-79-286
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-79-286-0.1mg0.1mg£481.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
Store antibody at -20˚C for up to one year.

Images

1 / 2
Western blot analysis of lysed extracts from HeLa cells using STAT3 (Ab-705).
2 / 2
<b>Top Image:</b> Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT3 (Ab-705).<b>Bottom Image:</b> Immunofluorescence staining of methanol-fixed HeLa cells using STAT3 (Ab-705) antibody (#21045, Red).
❮❯

Western blot analysis of lysed extracts from HeLa cells using STAT3 (Ab-705).
<b>Top Image:</b> Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using STAT3 (Ab-705).<b>Bottom Image:</b> Immunofluorescence staining of methanol-fixed HeLa cells using STAT3 (Ab-705) antibody (#21045, Red).

Documents

Further Information

Additional Names:
APRF, HIES, BSP1, MADH1, MADR1, APRF, Acute-phase response factor
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: IF:1:100~1:200
Background:
Transcription factor that binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.
Background References:
  • Heim M H, (1999) J Recept Signal Transduct Res. 19: 75-120. Takeda K, et al. (1997) Proc Natl Acad Sci USA. 94: 3801-3804. Catlett-Falcone R, et al. (1999) Immunity. 10: 105-115. Garcia R, et al. (1998) J Biomed Sci. 5: 79-85. Bromberg J F, et al. (1999) Cell. 98: 295-303.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
STAT3 (Ab-705) antibody was raised against a peptide sequence around aa.703~707 (A-P-Y-L-K) derived from Human STAT3.
NCBI Gene ID #:
6774
NCBI Official Name:
signal transducer and activator of transcription 3 (acute-phase response factor)
NCBI Official Symbol:
STAT3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
88 kDa
Protein Accession #:
NP_003141.2
Protein GI Number:
21618338
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Apoptosis,Cancer
SPECIFICITY:
This antibody detects endogenous level of total STAT3 protein.
Swissprot #:
P40763