Human IgA lambda (dimer)
| Code | Size | Price |
|---|
| P444 | 0.5 mg | £463.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
This product is shipped lyophilized at ambient temperature. After arrival store at +4°C. Prolonged storage may be at -20°C. The lyophilized content is reconstituted by adding 0.5 ml of sterile distilled water mixed gently by inversion until compl
Documents
Further Information
Background:
Confirmed by immunoelectrophoresis and double radial immunodiffusion (Ouchterlony). Not less than 98% as determined by agar-gel electrophoresis. This IgA1 consists mainly of dimers (as shown in non-reducing PAGE) and may contain traces of J chain. Purified human IgA1 lambda may be used as an IgA reference antigen, calibrator, coating protein and blocking agent in a variety of immunoassays including immunodiffusion, immunoelectrophoresis, ELISA, Western blotting, dot-immunobinding assays (DIBA), haemagglutination, and cell-binding assays.
Caution:
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
Concentration:
1 mg/ml
Field of Interest:
Immunology
Formulation:
Lyophilized, stable white powder No preservative added
Product:
0.5 ml solution of 1 mg/ml P 444.
Specificity:
Chromatographically purified Human IgA1 lambda, dimer.
References
Hansen IS, Hoepel W, Zaat SAJ, Baeten DLP, den Dunnen J. Serum IgA Immune Complexes Promote Proinflammatory Cytokine Production by Human Macrophages, Monocytes, and Kupffer Cells through Fc?RI-TLR Cross-Talk. J Immunol. 2017;199(12):4124-4131. doi:10.4049/jimmunol.1700883