anti-Fis1 pAb

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AdipoGen Life Sciences
Product Code: AG-25B-0007V
Product Group: Primary Antibodies
CodeSizePrice
AG-25B-0007V-C100100 ug£280.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunocytochemistry (ICC)
  • Immunoprecipitation (IP)
  • Western Blot (WB)
Shipping:
-20°C
Storage:
-20°C

Images

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Immunocytochemical staining and detection of endogenous Fis1 (red) (right) and endogenous mitochondrial Hsp70 (green) (left) in methanol fixed HeLa cells using anti-Fis1, pAb (Prod. No. AG-20B-0007V).Picture courtesy of P. Parone, University of G
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Immunocytochemical staining and detection of endogenous Fis1 (red) (right) and endogenous mitochondrial Hsp70 (green) (left) in methanol fixed HeLa cells using anti-Fis1, pAb (Prod. No. AG-20B-0007V).Picture courtesy of P. Parone, University of G

Documents

Further Information

Alternate Names/Synonyms:
Mitochondrial Fission 1 Protein; Tetratricopeptide Repeat Protein 11; TTC 11
Concentration:
1mg/ml
EClass:
32160000
Form (Short):
liquid
Formulation:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Handling Advice:
After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.
Immunogen:
Recombinant human Fis1.
Long Description:
Polyclonal Antibody. Recognizes human, mouse and rat Fis1. Source: Rabbit. Applications: ICC, IP, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Fis1 promotes the fragmentation of the mitochondrial network and its perinuclear clustering. It can induce cytochrome c release from mitochondria to the cytosol, ultimately leading to apoptosis. It also mediates peroxisomal fission.
NCBI, Uniprot Number:
Q9Y3D6
Other data:
This purified antiserum is replacing the product AG-25B-0007 Fis-1 pAb (neat antiserum) with same specifications.
Package Type:
Plastic Vial
Product Description:
Fis1 promotes the fragmentation of the mitochondrial network and its perinuclear clustering. It can induce cytochrome c release from mitochondria to the cytosol, ultimately leading to apoptosis. It also mediates peroxisomal fission.
Source / Host:
Rabbit
Specificity:
Recognizes human, mouse and rat Fis1.
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 1 year after receipt when stored at -20°C.

References

hFis1, a novel component of the mammalian mitochondrial fission machinery: D.I. James, et al.; J. Biol. Chem. 278, 36373 (2003) | A role for Fis1 in both mitochondrial and peroxisomal fission in mammalian cells: A. Koch, et al.; Mol. Biol. Cell 16, 5077 (2005) | The Novel Tail-anchored Membrane Protein Mff Controls Mitochondrial and Peroxisomal Fission in Mammalian Cells.: S. Gandre-Babbe & AM. van der Bliek; Mol. Biol. Cell 6, 2402 (2008)