Opipramol
| Code | Size | Price |
|---|
| CDX-O0042-M010 | 10 mg | £72.00 |
Quantity:
| CDX-O0042-M050 | 50 mg | £194.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
NSC 169867; BRN 0627076; 2-{4-[3-(5H-Dibenzo[b,f]azepin-5-yl)propyl]-1-piperazinyl}ethanol
Appearance:
White powder.
CAS:
315-72-0
Class:
9
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07,GHS09
Handling Advice:
Keep cool and dry.Protect from light and moisture.
Hazards:
H302 , H410
InChi:
InChI=1S/C23H29N3O/c27-19-18-25-16-14-24(15-17-25)12-5-13-26-22-8-3-1-6-20(22)10-11-21-7-2-4-9-23(21)26/h1-4,6-11,27H,5,12-19H2
InChiKey:
YNZFUWZUGRBMHL-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 315-72-0. Formula: C23H29N3O. MW: 363.5. Synthetic. Tricyclic antidepressant and anxiolytic compound. Acts as a high affinity sigma receptor agonist, primarily at the sigma1 subtype, but also at the sigma2 subtype with somewhat lower affinity. Shows a low to moderate antagonistic affinity for the D2, 5-HT2, H1, H2, and muscarinic acetylcholine receptors. H1 and H2 receptor antagonism account for its antihistamine effects, and muscarinic acetylcholine receptor antagonism is responsible for its anticholinergic properties.
MDL:
MFCD00865455
Molecular Formula:
C23H29N3O
Molecular Weight:
363.5
Package Type:
Vial
PG:
III
Precautions:
P273, P501
Product Description:
Tricyclic antidepressant and anxiolytic compound. Acts as a high affinity sigma receptor agonist, primarily at the sigma1 subtype, but also at the sigma2 subtype with somewhat lower affinity. Shows a low to moderate antagonistic affinity for the D2, 5-HT2, H1, H2, and muscarinic acetylcholine receptors. H1 and H2 receptor antagonism account for its antihistamine effects, and muscarinic acetylcholine receptor antagonism is responsible for its anticholinergic properties.
Purity:
>98% (HPLC)
Signal word:
Warning
SMILES:
OCCN1CCN(CCCN2C3=CC=CC=C3C=CC3=CC=CC=C23)CC1
Solubility Chemicals:
Soluble in chloroform.
Source / Host:
Synthetic.
Transportation:
Excepted Quantity
UN Nummer:
UN 3077
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) T.S. Rao, et al.; Neuropharmacology. 29, 1191 (1990) | (2) T.S. Rao, et al.; Neuropharmacology. 29, 1199 (1990) | (3) H.J. Moller, et al.; J. Clin. Psychopharmacol. 21,59 (2001) | (4) G. Holoubek & W.E. Muller; J. Neural Transm. 110, 1169 (2003) | (5) W.E. Muller, et al.; Pharmacopsychiatry 37, S189 (2004)