BEP

2-Bromo-1-ethyl-pyridinium tetrafluoroborate

White powder.

878-23-9

32160000

liquid

Keep cool and dry.Protect from light and moisture.

InChI=1S/C7H9BrN.BF4/c1-2-9-6-4-3-5-7(9)8;2-1(3,4)5/h3-6H,2H2,1H3;/q+1;-1

YJDXVQLBIAJTHP-UHFFFAOYSA-N

Chemical. CAS: 878-23-9. Formula: C7H9BBrF4N. MW: 273.86. Synthetic Efficient coupling reagent for the synthesis of sterically hindered amides, especially peptides. In terms of reactivity and racemization-suppressing capability, this pyridinium-type reagent, BEP, proved to be more efficient than commonly used uronium- and phosphonium-type reagents, such as HBTU, BOP, and PyBroP, for the synthesis of hindered peptides containing N-methylated or Calpha,Calpha-dialkylated amino acid residues. BEP was also proven to be an efficient reagent for the synthesis of esters, especially active esters and hindered esters, and tert-butyl esters.

MFCD00060046

C7H9BBrF4N

273.86

Vial

Efficient coupling reagent for the synthesis of sterically hindered amides, especially peptides. In terms of reactivity and racemization-suppressing capability, this pyridinium-type reagent, BEP, proved to be more efficient than commonly used uronium- and phosphonium-type reagents, such as HBTU, BOP, and PyBroP, for the synthesis of hindered peptides containing N-methylated or Calpha,Calpha-dialkylated amino acid residues. BEP was also proven to be an efficient reagent for the synthesis of esters, especially active esters and hindered esters, and tert-butyl esters.

>97% (Titration)

[F-].FB(F)F.CC[N]1=C(Br)C=CC=C1

Soluble in water.

Synthetic

Non-hazardous

Biochemical Reagents

12352200

Stable for at least 2 years after receipt when stored at -20°C.