Tetracycline hydrochloride
| Code | Size | Price |
|---|
| CDX-T0096-G005 | 5 g | £35.00 |
Quantity:
| CDX-T0096-G025 | 25 g | £84.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
Ambient
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
2-Naphthacenecarboxamide
Appearance:
Yellow to orange powder.
CAS:
64-75-5
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Keep cool and dry.Protect from light and moisture.
Hazards:
H315, H319, H335
InChi:
InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
InChiKey:
XMEVHPAGJVLHIG-FMZCEJRJSA-N
Long Description:
Chemical. CAS: 64-75-5. Formula: C22H24N2O8 . HCl. MW: 480.9. Synthetic Tetracycline is a broad-spectrum antibiotic that prevents bacterial growth by inhibiting protein synthesis. It binds to a single site in the 30S ribosomal subunit which prevents attachment of aminoacyl tRNA to the ribosomal acceptor site. It is used in cell biology as a selective agent in cell culture systems. Tetracycline is toxic to prokaryotic and eukaryotic cells and selects for cells harboring the bacterial tetR gene, which are resistant to the antibiotic.
MDL:
MFCD00078142
Molecular Formula:
C22H24N2O8 . HCl
Molecular Weight:
480.9
Package Type:
Vial
Precautions:
P261, P305, P351, P338
Product Description:
Tetracycline is a broad-spectrum antibiotic that prevents bacterial growth by inhibiting protein synthesis. It binds to a single site in the 30S ribosomal subunit which prevents attachment of aminoacyl tRNA to the ribosomal acceptor site. It is used in cell biology as a selective agent in cell culture systems. Tetracycline is toxic to prokaryotic and eukaryotic cells and selects for cells harboring the bacterial tetR gene, which are resistant to the antibiotic.
Purity:
>99% (HPLC)
Signal word:
Warning
SMILES:
Cl.[H][C@@]12C[C@@]3([H])C(=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)C2N(C)C)C(=O)C1=C(O)C=CC=C1[C@@]3(C)O
Solubility Chemicals:
Soluble in water (10 mg/ml), DMSO, methanol or 0.1 N HCl (10 mg/ml).
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) J. Degenkolb, et al.; Antimicrob. Agents. Chemother. 35, 1591 (1991) | (2) D.N. Wilson; Crit. Rev. Biochem. Mol. Biol. 44, 393 (2009)
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