Janus kinase 2 (phospho Tyr972) Antibody
| Code | Size | Price |
|---|
| PSI-39-867-0.05mg | 0.05mg | £782.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
Janus kinase 2-pY972-phospho specific, Janus kinase 2,
Application Note:
ELISA, Western (immuno) blotting, Immunostaining (in testing)
Background:
Janus Kinase 2 (JAK2) is essential for signaling thorough a variety of cytokine receptors. Phosphorylation of JAK is essential for downstream signaling. JAK kinases are known to phosphorylate several substrate including members of the STAT family of proteins
Background References:
- Issam McDoom, Xianyue Ma, Annet Kirabo, Kuang-Yung Lee, David A. Ostrov and Peter P. Sayeski., Identification of Tyrosine 972 as a Novel Site of Jak2 Tyrosine Kinase Phosphorylation and Its Role in Jak2 Activation., Biochemistry, 2008, 47 (32), pp 8326-8334
- Parganas E, Wang D, Stravopodis D, Topham DJ, Marine JC, Teglund S, Vanin EF, Bodner S, Colamonici OR, van Deursen JM, Grosveld G, Ihle JN., Jak2 is essential for signaling through a variety of cytokine receptors., Cell. 1998 May 1;93(3):385-95
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
A synthetic peptide corresponding to the pY972 region.
Modifications:
Phospho-Specific
NCBI Gene ID #:
12643404
NCBI Official Name:
Janus kinase 2
NCBI Official Symbol:
APP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
BAG63863
Protein GI Number:
12643404
Purification:
Affinity Purified
Research Area:
Phospho-Specific
Swissprot #:
O60674
User NOte:
Optimal dilutions for each application to be determined by the researcher.