KMO Antibody
| Code | Size | Price |
|---|
| PSI-39-869-0.1mg | 0.1mg | £782.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
317G22.1, KMO_HUMAN, Kynurenine 3 hydroxylase, Kynurenine 3 monooxygenase (kynurenine 3 hydroxylase), Kynurenine 3 monooxygenase, Kynurenine 3-hydroxylase, Kynurenine 3-monooxygenase, RP1-317G22.1, AI046660,
Application Note:
ELISA, Western (immuno) blotting, Immunostaining (in testing)
Background:
Kynurenine 3-monooxygenase (KMO) catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). The enzyme is required for synthesis of quinolinic acid. Quinolinic acid ia a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development.
Background References:
- Eniko Vamosa, Arpad Pardutza, Peter Klivenyia, Jozsef Toldib and Laszlo Vecsei, The role of kynurenines in disorders of the central nervous system: Possibilities for neuroprotection. 2009 Journal of the Neurological Sciences Article in Press, Corrected Proof available on line
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
A synthetic peptide corresponding to an internal region between amino acids 200-299.
NCBI Gene ID #:
98256
NCBI Official Name:
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
NCBI Official Symbol:
APP
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
EDL13209
Protein GI Number:
81879610
Purification:
Affinity Purified
Research Area:
Cancer
Swissprot #:
Q91WN4
User NOte:
Optimal dilutions for each application to be determined by the researcher.