TENM3 Antibody
| Code | Size | Price |
|---|
| PSI-8151-0.02mg | 0.02mg | £150.00 |
Quantity:
| PSI-8151-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
TENM3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Documents
Further Information
Additional Names:
Teneurin transmembrane protein 3, teneurin-3, ODZ3, TEN-M3, TNM3, MCOPCB9
Application Note:
TENM3 antibody can be used for detection of TENM3 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Antibody validated: Western Blot in human samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
Background:
The teneurin transmembrane protein 3 (TENM3) is a member of a family of four neuronal cell surface proteins homologous to the Drosophila pair-rule gene Ten-m (1,2). TENM3 is expressed in cartilaginous cells during postnatal growth in mice (3), as well as the adult eye and optic stalk (4). Homozygous null mutations in TENM3 causes microphthalmia in humans (5).
Background References:
- Ben-Zur T and Wides R. Mapping homologs of Drosophila odd oz (odz): Doc4/Odz to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25. Genomics 1999; 58:102-3.
- Rubin BP, Tucker RP, Martin D, et al. Tenurins: a novel family of neuronal cell surface proteins in vertebrates, homologous to the Drosophila pair-rule gene Ten-m. Dev. Biol. 1999; 216:195-209.
- Murakami T, Fukunaga T, Takeshita N, et al. Expression of Ten-m/Odz3 in the fibrous layer of madibular condylar cartilage during postnatal growth in mice. J. Anat. 2010; 217:236-44.
- Ben-Zur T, Feige E, Motro B, et al. The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles. Dev. Biol. 2000; 217:107-20.
Buffer:
TENM3 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
TENM3 antibody was raised against a 17 amino acid peptide near the amino terminus of human TENM3.
The immunogen is located within the first 50 amino acids of TENM3.
The immunogen is located within the first 50 amino acids of TENM3.
NCBI Gene ID #:
55714
NCBI Official Name:
teneurin transmembrane protein 3
NCBI Official Symbol:
TENM3
NCBI Organism:
homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
Predicted: 297 kDa
Observed: 300 kDa
Observed: 300 kDa
Protein Accession #:
NP_001073946
Protein GI Number:
122937400
Purification:
TENM3 antibody is affinity chromatography purified via peptide column.
Research Area:
Stem Cell,Neuroscience
SPECIFICITY:
TENM3 antibody is human, mouse and rat reactive. TENM3 antibody is predicted to not cross-react with other members of the TENM family.
Swissprot #:
Q9P273
User NOte:
Optimal dilutions for each application to be determined by the researcher.