STIM-1 Antibody
| Code | Size | Price |
|---|
| PSI-39-873-0.1mg | 0.1mg | £782.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Documents
Further Information
Additional Names:
Stromal Interaction Molecule-1 , GOK, TAM, IMD10, D11S4896E
Application Note:
ELISA, Western (immuno) blotting, Immunostaining (in testing)
Background:
STIM-1 is a component of the Ca sensor/channel. It associates with ORAI-1 and form a essential complex involved in store-operated channels. STIM1 activates Ca(2+) influx via Orai1 channels. Expression of STIM and Orai proteins are found in many cell types and knock-out mice lack viability.
Background References:
- Williams RT, Senior PV, Van Stekelenburg L, Layton JE, Smith PJ, Dziadek MA., Stromal interaction molecule 1 (STIM1), a transmembrane protein with growth suppressor activity, contains an extracellular SAM domain modified by N-linked glycosylation., Biochim Biophys Acta. 2002 Apr 1;1596(1):131-137
- Dziadek MA, Johnstone LS., Biochemical properties and cellular localisation of STIM proteins., Cell Calcium. 2007 Aug;42(2):123-32.
- Frischauf I, Schindl R, Derler I, Bergsmann J, Fahrner M, Romanin C.,. The STIM/Orai coupling machinery., Channels (Austin). 2008 Jul-Aug;2(4):261-8
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
A synthetic peptide corresponding to a region near the N-terminus.
NCBI Gene ID #:
6786
NCBI Official Name:
stromal interaction molecule 1
NCBI Official Symbol:
APP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
EAX02580
Protein GI Number:
209572721
Purification:
Affinity Purified
Research Area:
Immunology,Cancer
Swissprot #:
Q13586
User NOte:
Optimal dilutions for each application to be determined by the researcher.