SOX10 Antibody

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ProSci
Product Code: PSI-27-829
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-27-829-100ul100ul£662.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
For short periods of storage (days) store at 4°C. For longer periods of storage, store SOX10 antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.

Images

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Antibody used in WB on Human HepG2 at 0.25 ug/ml.
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Antibody used in IHC on Human Skin at 4-8 ug/ml.
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Antibody used in IHC on Human Kidney at 4-8 ug/ml.
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Antibody used in IHC on Human Kidney at 4-8 ug/ml.
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Antibody used in WB on Human Jurkat 2.5 ug/ml (Lane A: Primary Antibody and Lane B: Primary Antibody + Blocking Peptide ).
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Antibody used in WB on Human HepG2 at 0.25 ug/ml.
Antibody used in IHC on Human Skin at 4-8 ug/ml.
Antibody used in IHC on Human Kidney at 4-8 ug/ml.
Antibody used in IHC on Human Kidney at 4-8 ug/ml.
Antibody used in WB on Human Jurkat 2.5 ug/ml (Lane A: Primary Antibody and Lane B: Primary Antibody + Blocking Peptide ).

Documents

Further Information

Additional Names:
SOX10, DOM, WS4, PCWH, WS2E, WS4C
Application Note:
SOX10 antibody can be used for detection of SOX10 by ELISA at 1:62500. SOX10 antibody can be used for detection of SOX10 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. It acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.
Background References:
  • Collins, J.E., et al., (2004) Genome Biol. 5 (10), R84.
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SOX10.
NCBI Gene ID #:
6663
NCBI Official Name:
SRY (sex determining region Y)-box 10
NCBI Official Symbol:
SOX10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
NP_008872
Protein GI Number:
5902104
Purification:
Antibody is purified by protein A chromatography method.
Research Area:
Transcription
Swissprot #:
P56693
User NOte:
Optimal dilutions for each application to be determined by the researcher.