IL-23 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-559-0.002mg | 0.002mg | £300.00 |
Quantity:
| PSI-40-559-0.01mg | 0.01mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized IL-23 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-23 stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing
Documents
Further Information
Additional Names:
P19, SGRF, IL-23, IL-23A, IL23P19, UNQ2498/PRO5798, Interleukin-23 subunit alpha, Interleukin-23 subunit p19, IL-23 subunit alpha
Background:
IL-23 is a proinflammatory heterodimeric protein composed of two subunits, a unique p19 subunit and a p40 subunit, which is shared with IL-12. IL-23 is secreted by activated dendritic cells and macrophages, and signals though a receptor comprised of IL-23R complexed with IL-12Rβ1. IL-23 has been shown to enhance proliferation of memory T cells. It also stimulates the production of IFN-gamma in NK cells, induces IL-17 production, and drives Th17 mediated responses. Recombinant IL-23 is a 53.5 kDa heterodimeric protein consisting of two subunits, p19 (170 amino acids) and p40 (306 amino acids).*Manufactured using BTI-Tn-5B1-4 cells under license from the Boyce Thompson Institute for Plant Research, Inc.
Biological Activity:
Biological activity was measured by its ability to induce IL-17 secretion by mouse splenocytes. Endotoxin level is less than 0.1 ng per μg (1EU/μg).
NCBI Gene ID #:
51561
NCBI Official Name:
interleukin 23, alpha subunit p19
NCBI Official Symbol:
IL23A
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_057668.1
Protein GI Number:
7706702
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
(BTI-Tn-5B1-4) High-5 Insect cells
Swissprot #:
Q9NPF7