CD22 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-147-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-147-0.02mg | 0.02mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized CD22 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted CD22 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposin
Documents
Further Information
Additional Names:
SIGLEC2, SIGLEC-2, SIGLEC2, B-cell receptor CD22, B-lymphocyte cell adhesion molecule, BL-CAM
Background:
CD22 is a B-lineage restricted 135 kDa glycoprotein whose cell surface expression is limited to resting and activated B lymphocytes. The physiological role of CD22 is still unknown. Targeted disruption of CD22 in mice results in a reduced level of surface IgM on peripheral B cells suggesting a role for CD22 in limiting antigen receptor signaling. CD22 is a member of the Ig gene superfamily that uniquely binds a sialic acid-dependent ligand. Recombinant human CD22 is a soluble 75.0 kDa protein which corresponds to the extracellular domain of CD22.
Biological Activity:
Biological activity was determined by its ability to inhibit the proliferation of Raji cells. The expected ED50 for this effect is 10 - 17 μg/mL.
NCBI Gene ID #:
933
NCBI Official Name:
CD22 molecule
NCBI Official Symbol:
CD22
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001172030.1
Protein GI Number:
297374830
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
CHO cells
Swissprot #:
P20273