sCD27 Ligand Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-568-0.01mg | 0.01mg | £300.00 |
Quantity:
| PSI-40-568-0.05mg | 0.05mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized sCD27 Ligand recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted sCD27 Ligand stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any pro
Documents
Further Information
Additional Names:
CD27L, CD27LG, TNFSF7, CD27L, CD70 antigen, CD27 ligand, CD27-L
Background:
CD27 Ligand, a type II transmembrane protein, is a member of the TNF superfamily. It is expressed on activated T and B lymphocytes as well as NK cells. CD27L and its receptor (CD27) regulate the immune response by promoting T-cell expansion and differentiation, as well as NK enhancement. CD27 signaling can act as a co-stimulatory effector to sustain the survival of CD8+ T cells, primarily by inducing increased expression of the IL-2 gene. Full length human CD27L is a 193 amino acid protein, consisting of a 17 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 155 amino acid extracellular domain. Human soluble CD27L corresponds to the 155 amino acid extracellular domain of the full length CD27L protein. ProSci?s recombinant human sCD27L contains the extracellular domain plus an N-terminal His-Tag.
Biological Activity:
Biological activity was determined by its ability to stimulate human IL-8 production by human PBMC using a concentration range of 10.0-25.0 ng/mL. Note: Results may vary with PBMC donors. Endotoxin level is less than 0.1 ng per μg (1EU/μg).
NCBI Gene ID #:
970
NCBI Official Name:
CD70 molecule
NCBI Official Symbol:
CD70
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001243.1
Protein GI Number:
4507605
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
CHO cells
Swissprot #:
P32970