IL-1 alpha Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-240-0.002mg | 0.002mg | £300.00 |
Quantity:
| PSI-40-240-0.01mg | 0.01mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized IL-1 alpha recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-1 alpha is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any prot
Documents
Further Information
Additional Names:
IL1, IL-1A, IL1F1, IL1-ALPHA, Interleukin-1 alpha, Hematopoietin-1, IL-1 alpha
Background:
IL-1β is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant human IL-1α is an 18.0 kDa protein containing 159 amino acid residues.
Biological Activity:
The ED50 was determined by the dose - dependent stimulation of murine D10S cells is ≤ 0.001 ng/mL, corresponding to a specific activity of ≥ 1 x 109 units/mg.
NCBI Gene ID #:
3552
NCBI Official Name:
interleukin 1, alpha
NCBI Official Symbol:
IL1A
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000566.3
Protein GI Number:
27894330
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P01583