NNT-1 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-324-0.002mg | 0.002mg | £300.00 |
Quantity:
| PSI-40-324-0.01mg | 0.01mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized NNT-1 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted NNT-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, expos
Documents
Further Information
Additional Names:
CLC, NR6, BSF3, NNT1, BSF-3, CISS2, NNT-1, CLC, Cardiotrophin-like cytokine factor 1, B-cell-stimulating factor 3
Background:
NNT-1/BCSF-3 is a neurotrophic factor with B-cell stimulating capabilities. Expressed in lymph nodes and spleen, NNT-1/BCSF-3 binds and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member beta (LIFR-β) and induces tyrosine phosphorylation of these receptors. In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss and B cell hyperplasia associated with increased in serum IgG and IgM. Recombinant human NNT-1/BCSF-3 is a 22.4 kDa protein containing 199 amino acid residues.
Biological Activity:
NT - 1/BCSF - 3 weakly supports chick E8 DRG neurite outgrowth at a concentration of 1.0 ng/mL.
NCBI Gene ID #:
23529
NCBI Official Name:
cardiotrophin-like cytokine factor 1
NCBI Official Symbol:
CLCF1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001159684.1
Protein GI Number:
261245022
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q9UBD9