BAFF Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-305-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-305-0.02mg | 0.02mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized BAFF recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted BAFF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposin
Documents
Further Information
Additional Names:
DTL, BAFF, BLYS, CD257, TALL1, THANK, ZTNF4, TALL-1, TNFSF20, UNQ401/PRO738, Tumor necrosis factor ligand superfamily member 13B, B lymphocyte stimulator, BLyS
Background:
BAFF, a member of the TNF family of ligands, is expressed in T cells, macrophages, monocytes and dendritic cells. BAFF is involved in stimulation of B and T cell function, and is an important survival and maturation factor for peripheral B cells. BAFF signals through three different TNF receptors TACI, BCMA and BAFF-R. The human BAFF gene codes for a 285 amino acid type II transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain. Recombinant human soluble BAFF is a 153 amino acid polypeptide (17.0 kDa), which contains the TNF-like portion of the extracellular domain of BAFF.
Biological Activity:
Biological activity was determined by a mouse splenocyte survival assay. The expected ED50 for this effect is 0.5 - 2.0 μg/mL.
NCBI Gene ID #:
10673
NCBI Official Name:
tumor necrosis factor (ligand) superfamily, member 13b
NCBI Official Symbol:
TNFSF13B
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001139117.1
Protein GI Number:
224548983
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q9Y275