Betacellulin Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-192-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-192-0.02mg | 0.02mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized Betacellulin recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Betacellulin is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any
Documents
Further Information
Additional Names:
Probetacellulin, BTC
Background:
Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Human Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant human Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein.
Biological Activity:
The ED50 was determined by the dose - dependent stimulation of the proliferation of murine Balb/3T3 cells is ≤ 0.05 ng/mL, corresponding to a specific activity of ≥ 2 x 107units/mg.
NCBI Gene ID #:
685
NCBI Official Name:
betacellulin
NCBI Official Symbol:
BTC
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001720.1
Protein GI Number:
4502461
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P35070