CNTF Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-502-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-502-0.02mg | 0.02mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized CNTF recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted CNTF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposin
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Further Information
Additional Names:
HCNTF, Ciliary neurotrophic factor, CNTF
Background:
CNTF is a potent neural factor that was originally characterized as a vital factor for the survival of chick ciliary neurons in vitro. CNTF is also important for the survival of other neural cell types including primary sensory neurons, motor neurons, basal forebrain neurons and type 2 astrocytes. CNTF is highly conserved across species and exhibits cross-species bioactivity. Recombinant human CNTF is synthesized as a 199 amino acid polypeptide (22.7 kDa) lacking a hydrophobic N-terminal signal for secretion.
Biological Activity:
The ED50 was determined by the dose - dependent proliferation of human TF - 1 cells is < 2.0 ng/mL, corresponding to a specific activity of > 5 x 105 units/mg.
NCBI Gene ID #:
1270
NCBI Official Name:
ciliary neurotrophic factor
NCBI Official Symbol:
CNTF
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000605.1
Protein GI Number:
4758020
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P26441