IL-6 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-249-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-249-0.02mg | 0.02mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized IL-6 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-6 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposin
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Further Information
Additional Names:
HGF, HSF, BSF2, IL-6, IFNB2, Interleukin-6, B-cell stimulatory factor 2
Background:
IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.
Biological Activity:
Determined by its ability to stimulate the proliferation of mouse B9 cells.
NCBI Gene ID #:
3569
NCBI Official Name:
interleukin 6 (interferon, beta 2)
NCBI Official Symbol:
IL6
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000591.1
Protein GI Number:
10834984
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P05231