MDC Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-388-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-388-0.02mg | 0.02mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized MDC recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted MDC is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing
Documents
Further Information
Additional Names:
MDC, ABCD-1, SCYA22, STCP-1, DC/B-CK, A-152E5.1, MDC, C-C motif chemokine 22, CC chemokine STCP-1
Background:
MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity. Recombinant human MDC is an 8.1 kDa protein containing 69 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Biological Activity:
Biological activity was determined by its ability to chemoattract human T cells using a concentration range of 10.0 - 100.0 ng/mL.
NCBI Gene ID #:
6367
NCBI Official Name:
chemokine (C-C motif) ligand 22
NCBI Official Symbol:
CCL22
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_002981.2
Protein GI Number:
22538804
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
O00626