TL-1A Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-314-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-314-0.02mg | 0.02mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized TL-1A recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted TL-1A is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, expos
Documents
Further Information
Additional Names:
TL1, TL1A, VEGI, VEGI192A, TL1, Tumor necrosis factor ligand superfamily member 15, TNF ligand-related molecule 1
Background:
TL-1A belongs to the TNF superfamily of ligands. It is expressed predominantly in endothelial cells, and to a lesser extent in placenta, lung, kidney, skeletal muscle, pancreas, small intestine and colon. TL-1A inhibits endothelial cell proliferation and angiogenesis, and has been shown to induce NFkB activation, caspase activity, and apoptosis in responding cell lines. TL-1A interacts with TNFRSF25/DR3 receptor, but can also bind to a decoy receptor TNFRSF21/DR6. Recombinant human TL-1A is a 22.0 kDa polypeptide of 194 amino acid residues.
Biological Activity:
Biological activity was determined by its ability to stimulate IFN - gamma production by human PBMC using a concentration range of 10.0 - 100.0 ng/mL. Note: Results may vary with PBMC donors.
NCBI Gene ID #:
9966
NCBI Official Name:
tumor necrosis factor (ligand) superfamily, member 15
NCBI Official Symbol:
TNFSF15
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001191273.1
Protein GI Number:
324072728
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
O95150