Trefoil Factor 2 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-291-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-291-0.02mg | 0.02mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized Trefoil Factor 2 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Trefoil Factor 2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As w
Documents
Further Information
Additional Names:
SP, SML1, Trefoil factor 2, Spasmolysin, SP
Background:
The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute and chronic asthma (Nikolaidis, N.M. et al. Am. Journal Respir. Cell Mol. Biol. (2003) 4: 458-464). Recombinant human TFF2 is a 12.0 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.
Biological Activity:
Assay 1: Biological activity was determined by its ability to chemoattract human monocytes using a concentration range of 1.0 - 10.0 μg/mL.
Assay 2: Biological activity was determined by its ability to chemoattract human MCF - 7 cells using a concentration range of 1.0 - 10.0 ng/mL.
Assay 2: Biological activity was determined by its ability to chemoattract human MCF - 7 cells using a concentration range of 1.0 - 10.0 ng/mL.
NCBI Gene ID #:
7032
NCBI Official Name:
trefoil factor 2
NCBI Official Symbol:
TFF2
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_005414.1
Protein GI Number:
4885629
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q03403