VEGF-B Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-164-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-164-0.02mg | 0.02mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized VEGF-B recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted VEGF-B is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exp
Documents
Further Information
Additional Names:
VRF, VEGFL, VRF, Vascular endothelial growth factor B, VEGF-related factor, VEGF-B
Background:
VEGF-B, a member of the VEGF family, is a potent growth and angiogenic cytokine. It promotes DNA synthesis in endothelial cells, helps regulate angiogenesis and vascular permeability, and inhibits apoptosis in certain smooth muscle cells and neurons. VEGF-B is expressed in all tissues except the liver. It forms cell surfaced-associated disulfide linked homodimers and can form heterodimers with VEGF-A. There are two known isoforms, formed by alternative splicing, which have been designated VEGF-B167 and VEGF-B186. Both forms have identical amino-terminal sequences encoding a "cysteine knot? like structural motif, but differ in their carboxyl-terminal domains. Both VEGF-B isoforms signal only through the VEGFR1 receptor. Recombinant human VEGF-B is a 38.0 kDa disulfide-linked homodimeric protein consisting of two 167 amino acid polypeptide chains.
NCBI Gene ID #:
7423
NCBI Official Name:
vascular endothelial growth factor B
NCBI Official Symbol:
VEGFB
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001230662.1
Protein GI Number:
344179103
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P49765