WISP-1 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-217-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-217-0.02mg | 0.02mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized WISP-1 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted WISP-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exp
Documents
Further Information
Additional Names:
CCN4, WISP1c, WISP1i, WISP1tc, CCN4, WNT1-inducible-signaling pathway protein 1, CCN family member 4, WISP-1
Background:
WISP-1 is a member of the CCN family of secreted cysteine rich regulatory proteins. It is expressed in the heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen. WISP-1 is a beta catenin regulated protein that can contribute to tumorigenesis and has also been shown to play a role in bone development and fracture repair. Human WISP-1 is a 38.1 kDa protein containing 346 amino acid residues. It is composed of four distinct structural domains (modules); the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the thrombospondin type-1 repeat (TSP type-1) domain, and a C-terminal cystine knot-like (CTCK) domain.
Biological Activity:
The ED50 was determined by the dose - dependant proliferation of the MCF - 7 cell line. The expected ED50 for this effect is 1.0 - 3.0 μg/mL.
NCBI Gene ID #:
8840
NCBI Official Name:
WNT1 inducible signaling pathway protein 1
NCBI Official Symbol:
WISP1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001191799.1
Protein GI Number:
325910845
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
O95388