WISP-3 Recombinant Protein
Code | Size | Price |
---|
PSI-40-219-0.005mg | 0.005mg | £300.00 |
Quantity:
PSI-40-219-0.02mg | 0.02mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized WISP-3 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted WISP-3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exp
Documents
Further Information
Additional Names:
PPD, CCN6, LIBC, PPAC, UNQ462/PRO790/PRO956, WNT1-inducible-signaling pathway protein 3, CCN family member 6, WISP-3
Background:
WISP-3 is a member of the CCN family of secreted cysteine rich regulatory proteins. It is predominantly expressed in the adult kidney, testis and fetal kidney and weaker expression in placenta, ovary, prostate, small intestine, and skeletally-derived cells. WISP-3 is required for normal postnatal skeletal growth and cartilage homeostasis. Human WISP-3 is a 36.8 kDa protein containing 331 amino acid residues. It is composed of four distinct structural domains (modules); the IGF binding protein (IGFBP) domain, the von Willebrand Factor C (VWFC) domain, the thrombospondin type-1 repeat (TSP type-1) domain, and a C-terminal cystine knot-like (CTCK) domain.
Biological Activity:
The ED50 was determined by the dose - dependant proliferation of the MCF - 7 cell line. The expected ED50 for this effect is 0.2 - 0.3 μg/mL.
NCBI Gene ID #:
8838
NCBI Official Name:
WNT1 inducible signaling pathway protein 3
NCBI Official Symbol:
WISP3
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_003871.1
Protein GI Number:
4507925
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
O95389