Acrp30 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-326-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-326-0.025mg | 0.025mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized Acrp30 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Acrp30 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exp
Documents
Further Information
Additional Names:
ACDC, ADPN, APM1, APM-1, GBP28, ACRP30, ADIPQTL1, ACDC, Adiponectin, 30 kDa adipocyte complement-related protein
Background:
The gAcrp30 variant is a naturally occurring globular protein, obtained by proteolytic processing of adiponectin. Adiponectin is produced and secreted exclusively by adipocytes, and is a relatively abundant plasma protein, accounting for up to 0.05% of total serum protein. Like Adiponectin, Acrp30 is capable of decreasing hyperglycemia and reversing insulin resistance. Additionally, gAcrp30 has been shown to be an important factor in promoting fat loss by signaling muscle to absorb and burn Free-Fatty Acids (FFAs). The signaling receptors for adiponectin and gAcrp30 have recently been identified and names AdipoR1 and AdipoR2. AdipoR2 is predominantly expressed in the liver. This naturally occurring variant of human gAcrp30/Adipolean is an 18.1 kDa protein, containing 14 amino acids extra at the N-terminus of human gAcrp30/Adipolean.
Biological Activity:
Biological activity was determined by a cytotoxicity assay using M1 cells. The expected ED50 for this effect is 0.5 - 1.0 μg/mL.
NCBI Gene ID #:
9370
NCBI Official Name:
adiponectin, C1Q and collagen domain containing
NCBI Official Symbol:
ADIPOQ
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001171271.1
Protein GI Number:
295317372
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q15848