FGF-17 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-173-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-173-0.025mg | 0.025mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized FGF-17 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted FGF-17 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exp
Documents
Further Information
Additional Names:
HH20, FGF-13, Fibroblast growth factor 17, FGF-17
Background:
FGF-17 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-17 signals through the FGFR 1c, 2c, 3c, and 4. FGF-17 signals induction and patterning of embryonic brain. Recombinant human FGF-17 is a 22.7 kDa protein consisting of 195 amino acid residues.
Biological Activity:
Assay 1: The ED50 was determined by the dose - dependent stimulation of thymidine uptake by BaF3 cells expressing FGF - receptors is ≤ 0.5 ng/mL, corresponding to a specific activity of ≥ 2 x 106 units/mg. Assay 2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 10.0 ng/mL, corresponding to a specific activity of ≥ 1 x 105 units/mg.
NCBI Gene ID #:
8822
NCBI Official Name:
fibroblast growth factor 17
NCBI Official Symbol:
FGF17
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_003858.1
Protein GI Number:
4503693
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
O60258