IGF-BP7 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-321-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-321-0.025mg | 0.025mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized IGF-BP7 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IGF-BP7 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, e
Documents
Further Information
Additional Names:
AGM, PSF, TAF, FSTL2, IBP-7, MAC25, IGFBP-7, RAMSVPS, IGFBP-7v, IGFBPRP1, Insulin-like growth factor-binding protein 7, IGFBP-rP1
Background:
IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF induced differentiation of skeletal myoblasts, without affecting IGF induced proliferation. Additionally, IGF-BP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF independent mechanism, which causes a delay in the G1 phase of the cell cycle, and increased apoptosis. Recombinant human IGF-BP7 is a 26.4 kDa protein consisting of 257 amino acid residues.
NCBI Gene ID #:
3490
NCBI Official Name:
insulin-like growth factor binding protein 7
NCBI Official Symbol:
IGFBP7
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001240764.1
Protein GI Number:
359465608
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q16270