TWEAK Receptor Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-312-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-312-0.025mg | 0.025mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized TWEAK Receptor recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted TWEAK Receptor is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with
Documents
Further Information
Additional Names:
FN14, CD266, TWEAKR, FN14, Tumor necrosis factor receptor superfamily member 12A, Fibroblast growth factor-inducible immediate-early response protein 14, FGF-inducible 14
Background:
TWEAKR belongs to the TNF family of transmembrane proteins and contains a cytoplasmic "death domain", which can activated the cell's apoptotic machinery. It is expressed in the spleen, thymus, peripheral blood lymphocytes, colon, and small intestine. Signal transduction by TWEAKR can be activated by either the membrane anchored or the soluble TWEAK. Recombinant soluble TWEAKR is a 53 amino acid polypeptide (5.6 kDa) comprising the entire extracellular domain of the full length TWEAKR protein.
Biological Activity:
Biological activity was determined by its ability to inhibit TWEAK - induced weak cell death of HT29 cells. The expected ED50 for this effect is 1.0 - 3.0 μg/mL.
NCBI Gene ID #:
51330
NCBI Official Name:
tumor necrosis factor receptor superfamily, member 12A
NCBI Official Symbol:
TNFRSF12A
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_057723.1
Protein GI Number:
7706186
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q9NP84