Apo-SAA Recombinant Protein

ProSci
Product Code: PSI-40-129
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-40-129-0.01mg0.01mg£300.00
Quantity:
PSI-40-129-0.05mg0.05mg£428.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized Apo-SAA recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Apo-SAA is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, e

Documents

Further Information

Additional Names:
SAA, PIG4, SAA2, TP53I4, Serum amyloid A-1 protein, Amyloid fibril protein AA, SAA
Background:
Human apo-SAA is a 104 amino acid polypeptide that circulates primarily in association with high-density lipoproteins (HDL). The level of apo-SAA, normally 1-5 μg/mL in plasma, increases 500-1000 fold within 24 hours of an inflammatory stimulus and, under these conditions, is the most abundant HDL apo-lipoprotein. The human SAA gene codes for a 122 amino acid polypeptide, which contains an 18 amino acid N-terminal signal sequence. Recombinant Apo-SAA is a consensus SAA molecule corresponding to human apo-SAA1alpha except for the presence of an N-terminal methionine and substitution of asparagine for aspartic acid at position 60 and arginine for histidine at position 71(the later two substituted residues are present in apo-SAA2beta).
Biological Activity:
For most in vitro applications, apo - SAA exerts its biological activity in the concentration range of 10 - 50 μg/mL.
NCBI Gene ID #:
6288
NCBI Official Name:
serum amyloid A1
NCBI Official Symbol:
SAA1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000322.2
Protein GI Number:
40316912
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P0DJI8