TSG Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-205-0.01mg | 0.01mg | £300.00 |
Quantity:
| PSI-40-205-0.05mg | 0.05mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized TSG recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted TSG is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing
Documents
Further Information
Additional Names:
TSG, TSG, PSEC0250, Twisted gastrulation protein homolog 1
Background:
Twisted Gastrulation Protein (TSG) is a secreted BMP binding protein structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins, and can act either as a BMP4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP4/Chordin complex. Recombinant human TSG is a 199 amino acid 22.2 kDa protein containing the BMP/TGFβ binding portion of the full length TSG protein.
Biological Activity:
Biological activity was determined by its ability to neutralize BMP - 6 induced alkaline phosphatase production by ATDC chondrogenic cells. The expected ED50 for this effect is < 2.0 μg/mL of TSG.
NCBI Gene ID #:
57045
NCBI Official Name:
twisted gastrulation BMP signaling modulator 1
NCBI Official Symbol:
TWSG1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_065699.1
Protein GI Number:
10190664
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q9GZX9