NGF beta Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-495-0.02mg | 0.02mg | £300.00 |
Quantity:
| PSI-40-495-0.1mg | 0.1mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized NGF beta recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted NGF beta is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein,
Documents
Further Information
Additional Names:
NGFB, HSAN5, Beta-NGF, NGFB, Beta-nerve growth factor
Background:
Beta-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Beta-NGF is a potent neurotrophic factor that signals through its receptor beta-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Beta-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of Recombinant Human β-NGF is a non-covalently-linked homodimer of two 13.5 kDa, polypeptide monomers that each contain 120 amino acids and three disulfide bonds, which are required for biological activity.
Biological Activity:
Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The expected ED50 is ≤ 1.0 ng/mL, corresponding to a specific activity of ≥ 1 x 106 units/mg.
NCBI Gene ID #:
4803
NCBI Official Name:
nerve growth factor (beta polypeptide)
NCBI Official Symbol:
NGF
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_002497.2
Protein GI Number:
70995319
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P01138