ApoE3 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-136-0.1mg | 0.1mg | £300.00 |
Quantity:
| PSI-40-136-0.5mg | 0.5mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized ApoE3 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted ApoE3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, expos
Documents
Further Information
Additional Names:
AD2, LPG, LDLCQ5, Apolipoprotein E, Apo-E
Background:
ApoE3 belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in liver and brain and to some extent in almost every organ. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. E3 is the most common isoform and is present in 40-90% of the population. Recombinant human ApoE3 is a 34.4 kDa protein containing 300 amino acid residues.
Biological Activity:
Determined by its ability to stimulate the proliferation of human SH-SY5Y cells.
NCBI Gene ID #:
348
NCBI Official Name:
apolipoprotein E
NCBI Official Symbol:
APOE
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000032.1
Protein GI Number:
4557325
Purity:
Greater than 90% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P02649