ApoE4 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-138-0.1mg | 0.1mg | £300.00 |
Quantity:
| PSI-40-138-0.5mg | 0.5mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized ApoE4 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted ApoE4 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, expos
Documents
Further Information
Additional Names:
AD2, LPG, LDLCQ5, Apolipoprotein E, Apo-E
Background:
ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. In addition to facilitating solublization of lipids, these proteins help to maintain the structural integrity of lipoproteins, serve as ligands for lipoprotein receptors, and regulate the activity of enzymes involved in lipid metabolism. Significant quantities of ApoE are produced in liver and brain and to some extent in almost every organ. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Individuals heterozygous for the ApoE4 allele are at higher risk of late-onset Alzheimer?s disease. Recombinant human ApoE4 is a 34.4 kDa protein containing 300 amino acid residues.
NCBI Gene ID #:
348
NCBI Official Name:
apolipoprotein E
NCBI Official Symbol:
APOE
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000032.1
Protein GI Number:
4557325
Purity:
Greater than 90% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P02649