GM-CSF Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-593-0.02mg | 0.02mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized GM-CSF recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted GM-CSF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exp
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Further Information
Additional Names:
GMCSF, GMCSF, Granulocyte-macrophage colony-stimulating factor, Colony-stimulating factor, GM-CSF
Background:
GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites.
Biological Activity:
The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is = 0.1 ng/mL, corresponding to a specific activity of = 1 x 107 units/mg.
NCBI Gene ID #:
1437
NCBI Official Name:
colony stimulating factor 2 (granulocyte-macrophage)
NCBI Official Symbol:
CSF2
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000749.2
Protein GI Number:
27437030
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P04141