SCF Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-608-0.01mg | 0.01mg | £481.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized SCF recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted SCF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing
Documents
Further Information
Additional Names:
SF, MGF, SCF, FPH2, KL-1, Kitl, SHEP7, Kit ligand, Mast cell growth factor
Background:
SCF is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant human SCF is an 18.4 kDa polypeptide containing 165 amino acid residues, which corresponds to the sequence of the secreted soluble form of SCF.
Biological Activity:
The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is = 2.0 ng/mL, corresponding to a specific activity of = 5 x 105 units/mg.
NCBI Gene ID #:
4254
NCBI Official Name:
KIT ligand
NCBI Official Symbol:
KITLG
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000890.1
Protein GI Number:
4505175
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P21583