IL-34 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-560-0.002mg | 0.002mg | £300.00 |
Quantity:
| PSI-40-560-0.01mg | 0.01mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Human
Storage:
The lyophilized IL-34 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-34 stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing
Documents
Further Information
Additional Names:
IL-34, C16orf77, Interleukin-34, IL-34
Background:
IL-34 is a homodimeric cytokine that is expressed in a range of tissues including spleen, heart, brain, liver, kidney, lung, ovary, thymus, testis, small intestine, prostate and colon. IL-34 is a ligand for colony-stimulating factor-1 receptor (CSF1R), which also binds to CSF-1. It specifically binds CD14+ monocytes, promotes survival and proliferation of human peripheral blood monocytes, and stimulates macrophage colony formation by human bone marrow cells. IL-34, like human CSF-1 stimulates phosphorylation of MAPK1/ERK2 and MAPK3/ERK1. Recombinant human IL-34 is a 52.5 kDa homodimeric glycoprotein consisting of 460 amino acid residues, including a C-terminal His-Tag.
Biological Activity:
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
NCBI Gene ID #:
146433
NCBI Official Name:
interleukin 34
NCBI Official Symbol:
IL34
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001166242.1
Protein GI Number:
289666750
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
Q6ZMJ4