IL-12 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-419-0.002mg | 0.002mg | £300.00 |
Quantity:
| PSI-40-419-0.01mg | 0.01mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Storage:
The lyophilized IL-12 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-12 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, expos
Documents
Further Information
Additional Names:
p35, Ll12a, Il-12a, IL-12p35, Interleukin-12 subunit alpha, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL-12A
Background:
IL-12 is a potent regulator of cell mediated immune responses and it induces IFN-gamma production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue type mast cells. Among its biological activities IL-12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells and induces the development of IFN-gamma producing Th1 cells. Recombinant murine IL-12 is a 75.0 kDa heterodimeric glycoprotein consisting of disulfide-linked 35 kDa (p35) and 40 kDa (p40) subunits (506 total amino acid residues).
Biological Activity:
Determined by its ability to induce cell proliferation in T-cell enriched PBMCs. The expected ED50 is < 0.1 ng/ml, corresponding to a specific activity of > 1 x 107 units/mg.
NCBI Gene ID #:
16159
NCBI Official Name:
interleukin 12a
NCBI Official Symbol:
Il12a
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
NP_032377.1
Protein GI Number:
6680395
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
CHO cells
Swissprot #:
P43431