Cardiotrophin-1 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-441-0.002mg | 0.002mg | £300.00 |
Quantity:
| PSI-40-441-0.01mg | 0.01mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Storage:
The lyophilized Cardiotrophin-1 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Cardiotrophin-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As wit
Documents
Further Information
Additional Names:
CT-1, Cardiotrophin-1, CT-1
Background:
CT-1 is a member of the IL-6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL-11, IL-6 and possibly NNT-1/ BCSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Recombinant murine Cardiotrophin-1 is a 21.3 kDa protein consisting of 202 amino acid residues.
Biological Activity:
The ED50 was determined by the dose - dependent proliferation of TF - 1 cells was < 1.0 ng/mL, corresponding to a specific activity of > 1 x 106 units/mg.
NCBI Gene ID #:
13019
NCBI Official Name:
cardiotrophin 1
NCBI Official Symbol:
Ctf1
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
NP_031821.1
Protein GI Number:
6681075
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q60753