VEGF Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-491-0.002mg | 0.002mg | £300.00 |
Quantity:
| PSI-40-491-0.01mg | 0.01mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Target Species: Mouse
Storage:
The lyophilized VEGF recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted VEGF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposin
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Further Information
Additional Names:
Vpf, Vegf, Vascular endothelial growth factor A, Vascular permeability factor, VEGF-A
Background:
VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant murine VEGF is a 39.0 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
Biological Activity:
Biological activity was determined by the dose - dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0 - 5.0 ng/mL.
NCBI Gene ID #:
22339
NCBI Official Name:
vascular endothelial growth factor A
NCBI Official Symbol:
Vegfa
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
NP_001273985.1
Protein GI Number:
559767228
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q00731